How Much Protein on a GLP-1? Your Daily Gram Target by Body Weight

A gram target you can check yourself against, plus the practical problem nobody warns you about: hitting it when you're not hungry.

LockedIn is a tracking tool, not medical advice. It does not verify what you enter, and it does not recommend doses, schedules, or intake targets. Dose and medication decisions come from your prescriber. Nothing on this page is a substitute for their instructions.

The working range on this site is 1.2 to 1.6 grams of protein per kilogram of body weight per day, which comes out to roughly 0.55 to 0.73 grams per pound. That sits above the IOM's RDA of 0.8 g/kg for a sedentary adult and overlaps the bottom of the 1.4 to 2.0 g/kg the ISSN position stand gives for people training. For a 180 lb (82 kg) person that's about 98 to 131 grams a day. For a 140 lb (64 kg) person, about 76 to 102 grams. For a 250 lb (113 kg) person, about 136 to 181 grams.

Two things to know before you write a number down. First, that range comes from general weight-loss and protein research rather than any GLP-1 specific table, and it's a starting point rather than a prescription. Second, the kilogram figure matters: at higher body weights, some clinicians calculate from a target or adjusted weight instead of current scale weight, which lowers the result considerably. Your prescriber or a registered dietitian should set your actual target, especially if you have kidney disease, liver disease, are pregnant, or take other medications. I'm a developer who built a tracking app, not a clinician, and none of this is medical advice.

GLP-1 medications like semaglutide, tirzepatide, and liraglutide suppress appetite hard. Total intake drops fast, and protein is usually the first thing to fall off the plate. The protein requirement is the same one that applies in any deficit. What changes is how little food goes in. When weight comes off quickly, a meaningful share of it can be lean mass, and the ISSN position stand pairs protein intake with resistance training as what protects fat-free mass while you're eating less than you burn.

So the practical answer is: pick a gram number inside that range, write it down, then check what you're eating against it for a week.

Protein target from body weight

An estimate from a published range, not a prescription.

The gram target, worked out for common body weights

To convert on your own: divide your weight in pounds by 2.205 to get kilograms, then multiply by 1.2 for the low end and 1.6 for the high end.

Body weight1.2 g/kg1.6 g/kg
130 lb / 59 kg71 g94 g
150 lb / 68 kg82 g109 g
170 lb / 77 kg93 g123 g
190 lb / 86 kg103 g138 g
210 lb / 95 kg114 g152 g
230 lb / 104 kg125 g167 g
250 lb / 113 kg136 g181 g
280 lb / 127 kg152 g203 g

Where you sit inside the range usually depends on how much resistance training you're doing and how aggressive the calorie deficit is. If you're lifting several days a week you belong at the top of it, which is where the ISSN numbers start. The bottom is closer to a floor than a goal.

One caveat worth repeating. At 280 lb, 203 grams of protein is an enormous amount of food, and on a GLP-1 you may have nowhere near the appetite for it. That's part of why some clinicians calculate from an adjusted body weight instead of current weight. If the number in this table looks impossible, that's a good thing to bring to your prescriber or dietitian rather than something to white-knuckle through.

Why the number is hard to hit when your appetite disappears

Running the math takes ten seconds. Eating the result is where people get stuck.

On a GLP-1, gastric emptying slows and hunger signals go quiet. Intake often falls by several hundred calories a day without any deliberate restriction, and further in the days right after a dose increase. If you're eating 1,200 calories and your target is 130 grams of protein, protein alone accounts for 520 of those calories. That's 43 percent of your intake, which means almost every bite has to be doing work.

Usually the miss comes from a skipped meal rather than a bad food choice. You're not hungry at noon, you push lunch to 3pm, then you're full by 6pm, and the day ends at 55 grams. Do that five days a week and the shortfall in protein is proportionally much bigger than the shortfall in calories.

A few things that tend to help, none of them medical advice:

For reference: 4 oz of cooked chicken breast is roughly 35 g, a cup of nonfat Greek yogurt about 22 g, three large eggs about 19 g, a cup of 2 percent cottage cheese about 24 g, and a typical whey scoop 24 to 30 g. Four of those in a day gets you past 100 grams.

How to check what you're eating instead of guessing

When I started weighing food, I was well under what I would have guessed, and the first week of logging is where you find out by how much. The gap tends to come from a few predictable places: counting a chicken sandwich as the chicken and forgetting the bun is most of the mass, using a raw weight where the label was for cooked, or eyeballing a portion that turns out to be 3 oz instead of 6 oz.

You don't need to log forever. A week is usually enough to see the shape of the problem. You're looking for one thing: the gap between your average day and the number in the table above.

Two things make that week less annoying. A food database with real serving sizes, so you can pick "1 cup chopped" or "1 medium apple" instead of doing gram conversions in your head at the kitchen counter. And a barcode scanner, because the fastest accurate log is the one where you point a camera at the yogurt cup and move on.

Then set your protein number yourself rather than accepting whatever a default calculator hands you. A generic macro split that assigns 25 percent of calories to protein will give someone eating 1,100 calories a target of 69 grams, which is under 1.2 g/kg for anyone over about 127 pounds. On a GLP-1 the calorie number moves around week to week. The protein number should hold steady.

What this page doesn't answer, and who to ask

This gives you a gram range and a way to check yourself against it. It can't tell you whether that range is right for your body, your labs, or your medication.

Talk to your prescriber or a registered dietitian if any of these apply: you have reduced kidney function or a history of kidney disease, you have liver disease, you're pregnant or nursing, you're losing weight faster than your care team expected, you have persistent nausea or vomiting, or your intake has dropped so low that you're struggling to eat much of anything. Very low total intake on a GLP-1 is worth a call to your clinician.

Nothing here is dosing guidance. Your dose, your titration schedule, and how to administer the medication come from your prescriber and from the manufacturer's instructions for your specific product, and from nowhere else.

I built LockedIn to see my own numbers. I have no clinical training. The app tracks what you tell it, and it doesn't know anything about your bloodwork.

How LockedIn handles this

I built LockedIn to answer this exact question for myself. Protein is an editable target in Edit Goals, so if your dietitian says 130 grams, you type 130 instead of living with whatever a default split produced. There are 321,737 foods in the database, and for 267,238 of them you can log a real portion like "1 cup chopped" instead of converting to grams at the kitchen counter. Barcode scanning covers packaged food. Saved meals are the piece that helps most on a GLP-1: build your morning yogurt bowl once, then log the whole thing in one tap on every morning you eat the same three things again. On the medication side, the app logs doses, titration plans, dose-day reminders, and injection site rotation, and plots your doses on the weight trend so you can see where a dose change lines up with your intake. It records what you enter and nothing more. Follow your prescriber. LockedIn is free while it's in beta, runs on iPhone and in the browser, and food and macro logging will stay on the free tier.

Try it in the browser

Common questions

How many grams of protein per day should I eat on a GLP-1?

The working range on this site is 1.2 to 1.6 grams per kilogram of body weight per day, or roughly 0.55 to 0.73 grams per pound. That sits above the IOM's RDA of 0.8 g/kg and overlaps the bottom of the 1.4 to 2.0 g/kg the ISSN position stand gives for people training. It comes to about 98 to 131 grams for a 180 lb person. Your prescriber or a registered dietitian should set your actual target, especially if you have kidney or liver conditions.

Should I use my current weight or my goal weight to calculate protein?

Both approaches are used. Many calculators default to current weight, but some clinicians calculate from a target or adjusted body weight at higher starting weights, which produces a noticeably lower gram figure. If the number from current weight looks impossible to eat, raise it with your prescriber or dietitian rather than forcing it.

Why is protein emphasized so much on semaglutide or tirzepatide?

Because these medications suppress appetite enough that total intake drops sharply, and protein is usually the first thing to fall off the plate. When weight comes off fast, some of it can be lean mass, and the ISSN position stand pairs protein intake with resistance training as what protects fat-free mass while you're eating less than you burn.

What if I can't eat enough protein because I feel too full?

This is common, especially in the days right after a dose increase. Many people front-load protein earlier in the day, eat the protein portion of a meal first, and lean on softer or liquid sources like Greek yogurt, cottage cheese, or shakes. If your total intake stays very low or you have persistent nausea or vomiting, contact your prescriber.

Does LockedIn set my protein target for me?

LockedIn generates a starting plan during onboarding, but calories, protein, carbs, and fat are all editable in Edit Goals, so you can enter whatever number you and your prescriber or dietitian decide on. The app tracks what you log and doesn't give medical or dosing advice.

Track it instead of guessing at it

LockedIn puts food, GLP-1 doses, workouts and weight in one place. Free while it is in beta.